NEW NAD+ PROTOCOL

Combined Protocol (IV + IM/SC)

A very popular clinical structure:

Phase 1 – NAD+ Loading

• 250–500mg IV
• 1–2× weekly × 2–4 weeks
• PLUS 100–200mg SC on non-IV days (loading dose)

Phase 2 – Stabilisation

• 500–750mg IV every 2–4 weeks
• OR 150–250mg IM weekly (stabilisation dose)

Phase 3 – Maintenance

• Monthly IV or weekly IM

Contraindications & Precautions

❌ Pregnancy & breastfeeding

❌ Severe anxiety disorder (relative – may worsen during infusion)

❌ Uncontrolled hypertension

❌ Active infection

❌ Severe liver or renal dysfunction

❌ Acute migraines during infusion season

Caution

• SSRIs, SNRIs, antipsychotics → monitor for overstimulation
• Beta-blockers → may mask physiological response
• Thyroid disorders → NAD+ may alter energy perception

Side Effects

Usually rate-dependent:

• Nausea
• Chest tightness
• Head pressure
• Tingling
• GI discomfort
• Warmth/flushing
• Anxiety or "wired" sensation
• Fatigue post infusion (rare)

Manage by slowing rate — symptoms disappear in minutes - keep rate slow