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IV/Vitamins

MYERS COCKTAIL IV INFUSION

Last updated 4/30/2026

MYERS COCKTAIL IV INFUSION

Clinical Purpose

The Myer's Cocktail IV is a foundational micronutrient infusion designed to restore cellular energy, support immunity, reduce fatigue, and promote metabolic balance. It combines vitamins, minerals, and coenzymes delivered intravenously for optimal absorption and bioavailability.

MYER'S MAKE UP (can vary from different pharmacies)

  • VITAMIN C (ASCORBIC ACID) 500MG/ML
  • MAGNESIUM SULPHATE 500MG/ML
  • THIAMINE (B1) 100MG/ML
  • RIBOFLAVIN-5-PHOSPHATE (B2) 2MG/ML
  • NIACINAMIDE (B3) 100MG/ML
  • DEXPANTHENOL (B5) 250MG/ML
  • PYRIDOXINE (B6) 100MG/ML
  • METHYLCOBALAMIN (B12) 1MG/ML
  • CALCIUM GLUCONATE 100MG/ML

Please adhere to Standard Wellness Dose per your dose reference guide

💧 Diluent: 500ml Hartmann's Sodium Chloride

🕒 Infusion Time: 30–45 minutes (slow IV drip)

Contraindications / Cautions

⚠

  • Known hypersensitivity to any ingredient
  • Severe renal impairment or acute dehydration
  • Uncontrolled hypertension or arrhythmia
  • Pregnancy or breastfeeding (safety data limited)
  • G6PD deficiency (use caution with high-dose Vitamin C)

Potential Side Effects

🩺

  • Transient warmth or flushing (from Magnesium/Niacinamide)
  • Metallic taste or mild nausea
  • Localised vein irritation (rare)
  • Dizziness or hypotension if infused too rapidly

Management: Slow or stop infusion immediately if symptomatic. Monitor BP and HR. Provide reassurance and maintain observation for 15 minutes post-infusion.

Frequency

⏱

  • Initial Phase: Weekly for 4–6 weeks
  • Maintenance: Every 2–4 weeks depending on client needs

Mechanism of Action

🧠

The Myer's Cocktail replenishes key cellular cofactors (B-vitamins and magnesium) required for the Krebs cycle, promoting ATP production, neurotransmitter balance, and immune system function. Vitamin C and Niacinamide enhance redox balance and NAD⁺ synthesis, improving fatigue and recovery.

Compliance Statement

🧾

This protocol aligns with TGA & AHPRA professional communication guidelines and IV Therapy Academy Australia clinical governance standards. Use only under the direction of an authorised prescriber within scope of practice.

Australian Injectable Drugs Handbook

VITAMIN C (ASCORBIC ACID) - See Vitamin C

MAGNESIUM SULPHATE - See Magnesium Sulphate

THIAMINE (B1)

STABILITY

Store below 25 °C. Protect from light.1,2

Nil Incompatibility

REFERENCES

  1. Product information. Available from www.tga.gov.au. Accessed 07/11/2024.
  2. Thiamine Sterop. Product information. North Sydney: Boucher & Muir Pty Ltd. Approved 10/07/2024.
  3. Water-soluble vitamin deficiencies [June 2023]. In: Therapeutic Guidelines [internet]. Melbourne: Therapeutic Guidelines Limited; June 2024.
  4. Latt N, Dore G. Thiamine in the treatment of Wernicke encephalopathy in patients with alcohol use disorders. Intern Med J 2014; 44: 911-5.
  5. ASHP Injectable drug information 2021. Bethesda, MD: American Society of Health-System Pharmacists; 2021.
  6. Paediatric Formulary Committee. BNF for children. London: BMJ group and Pharmaceutical Press; 2024.
  7. Thiamine hydrochloride. In: IV Index [internet]. Trissel's 2 clinical pharmaceutics database (parenteral compatibility) Greenwood Village, CO: IBM Watson Health. Accessed 08/08/2022.

DEXPANTHENOL (B5)

No Data on Dexpanthenol in AIDH

PYRIDOXINE (B6)

STABILITY

Store below 25 °C. Protect from light. Do not refrigerate or freeze.1

No Incompatibility

REFERENCES

  1. Australian product information. Braeside, VIC: Biological Therapies. Updated 27/04/2020. Accessed 22/03/2023.
  2. Kerr S. pH of injectable products [email]. Braeside, Vic: Biological Therapies; 18/01/2023.
  3. Isoniazid poisoning [August 2020]. In: Therapeutic Guidelines [internet]. Melbourne: Therapeutic Guidelines Limited; August 2022.
  4. Lexicomp pediatric and neonatal dosage handbook. 29th ed. Hudson, OH: UpToDate Inc; 2022-2023.
  5. Pyridoxine hydrochloride. In: IV index [internet]. Trissel's 2 clinical pharmaceutics database (parenteral compatibility). Ann Arbour, MI: Merative. Accessed 11/02/2023

METHYLCOBALAMIN (B12)

See Methylcobalamin B12

CALCIUM GLUCONATE

STABILITY

Vial: store below 30 °C. Do not refrigerate.1

Infusion solution: complete the infusion within 24 hours.1

No Incompatibility with other compounds

REFERENCES

  1. Product information. Available from www.tga.gov.au. Accessed 29/01/2024.
  2. ASHP Injectable drug information 2021. Bethesda, MD: American Society of Health-System Pharmacists; 2021.
  3. Electrolyte abnormalities [March 2021]. In Therapeutic Guidelines [internet]. Melbourne: Therapeutic Guidelines Limited; June 2023.
  4. Hypocalcaemia [August 2022]. In: Therapeutic Guidelines [internet]. Melbourne: Therapeutic Guidelines Limited; June 2023.
  5. Phelps SJ, Hagemann TM, Lee KR, Thompson AJ. Pediatric injectable drugs. The teddy bear book. 11th ed. Bethesda, MD: American Society of Health-System Pharmacists; 2018.
  6. Medical information. Plasma-Lyte 148 compatibility summary. Toongabbie, NSW: Baxter; March2022.
  7. Trissel LA, Leissing NC. Trissel's Tables of physical compatibility. Lake Forest IL: Multimatrix; 1996.
  8. Calcium gluconate. In: IV index [internet]. Trissel's 2 clinical pharmaceutics database (parenteral compatibility). Ann Arbour, MI: Merative. Accessed 09/05/2023.
  9. Trissel LA. Handbook on injectable drugs. 16th ed. Bethesda, MD: American Society of Health-System Pharmacists; 2011.

RIBOFLAVIN-5-PHOSPHATE (B2)

No Data on Riboflavin-5-Phosphate in AIDH

NIACINAMIDE (B3)

No Data on Niacinamide in AIDH