GLYCINE

Dosage Ranges

Medical/parenteral nutrition use (reference point):

Adults typically receive 0.4–0.7 g/kg/day as part of amino acid solutions in TPN (not as standalone glycine).

IV Wellness Practice (adjunct amino acid):

• Dose range: 100–500 mg IV per drip
• Equivalent to: 2–10 mL of 50 mg/mL solution
• Dilution: add to 250–500 mL carrier fluid (0.9% NaCl, Hartmann's, or CSL)
• Infusion time: 30–60 minutes
• Frequency: fortnightly depending on client needs

Clinical / Wellness Benefits

• Neurotransmitter support: calming effect (glycine is an inhibitory neurotransmitter)
• Sleep & relaxation: promotes deeper sleep and reduced anxiety
• Detoxification & methylation: supports glutathione synthesis (glycine + cysteine + glutamate)
• Collagen support: structural amino acid for skin, joints, connective tissue
• Metabolic health: may improve insulin sensitivity and support energy metabolism

Safety & Precautions

• Generally well tolerated in IV nutrition settings
• Mild side effects (rare): nausea, lightheadedness if infused too quickly
• Avoid very rapid IV push — always dilute
• Caution in renal impairment (amino acid clearance may be reduced)
• Consider baseline renal and liver function tests if used repeatedly

Australian Injectable Drugs Handbook

https://aidh.hcn.com.au/

There is no data for Glycine with AIDH