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IV/Vitamins

B COMPLEX PLUS (B1/B2/B3/B5/B6) + (B12)

Last updated 4/30/2026

B COMPLEX PLUS (B1/B2/B3/B5/B6) + (B12)

Refer to Protocols and dosage for B Complex on previous page.

Vitamin B12 (Methylcobalamin):

  • Methylcobalamin: 1,000–5,000 mcg IV
  • Can be given as:
  • Added into drip with B Complex (when purchased together)
  • Or slow IV push diluted in saline (separately)

B COMPLEX PLUS

Has added B6 (Pyridoxine) & B12 (Methylcobalamin)

Please refer to your Quick Reference Guide for Dosage Instructions

Infusion Protocol

  • Dilute into 250–500 mL carrier fluid (0.9% Normal Saline or Hartmann's).
  • Infuse over 30–60 minutes.
  • Frequency: weekly to fortnightly depending on clinical goals.

Benefits

  • Energy production: synergy of B vitamins + B12 for ATP & metabolism
  • Nervous system support: cognition, memory, stress, mood regulation
  • Detox & methylation: B12 and folate pathways supported by B Complex
  • Hair, skin, nails: stronger regenerative effects when combined
  • Fatigue & recovery: useful post-illness, for athletes, or high-stress clients

Safety & Notes

  • B Complex: infuse slowly to avoid vein irritation or nicotinamide flush.
  • B12: well tolerated; rare hypersensitivity. Hydroxocobalamin may cause pink-red urine for 24–48h.
  • Avoid repeated high-dose pyridoxine (B6) as it can cause neuropathy with chronic overuse.
  • Always ensure doctor prescription, pharmacy-compounding, and TGA compliance.
  • Obtain baseline bloods (B12, folate, homocysteine, CBC, renal/liver function) if doing regular therapy.

Australia Injectable Drugs Handbook

https://aidh.hcn.com.au/browse/c/cyanocobalamin (B12)

Please refer to B-Complex for reference to B1/B2/B3/B5)

STABILITY

Store below 25 °C. Protect from light. Do not refrigerate or freeze.1

REFERENCES

Product information. Available from www.tga.gov.au. Accessed 24/08/2022.

Lexicomp pediatric and neonatal dosage handbook. 29th ed. Hudson, OH: UpToDate Inc; 2022-2023.

ASHP Injectable drug information 2021. Bethesda, MD: American Society of Health-System Pharmacists; 2021.