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# GLYCINE

## Dosage Ranges

### Medical/parenteral nutrition use (reference point):

Adults typically receive 0.4–0.7 g/kg/day as part of amino acid solutions in TPN (not as standalone glycine).

### IV Wellness Practice (adjunct amino acid):

- **Dose range:** 100–500 mg IV per drip
- **Equivalent to:** 2–10 mL of 50 mg/mL solution
- **Dilution:** add to 250–500 mL carrier fluid (0.9% NaCl, Hartmann's, or CSL)
- **Infusion time:** 30–60 minutes
- **Frequency:** fortnightly depending on client needs

## Clinical / Wellness Benefits

- Neurotransmitter support: calming effect (glycine is an inhibitory neurotransmitter)
- Sleep & relaxation: promotes deeper sleep and reduced anxiety
- Detoxification & methylation: supports glutathione synthesis (glycine + cysteine + glutamate)
- Collagen support: structural amino acid for skin, joints, connective tissue
- Metabolic health: may improve insulin sensitivity and support energy metabolism

## Safety & Precautions

- Generally well tolerated in IV nutrition settings
- Mild side effects (rare): nausea, lightheadedness if infused too quickly
- Avoid very rapid IV push — always dilute
- Caution in renal impairment (amino acid clearance may be reduced)
- Consider baseline renal and liver function tests if used repeatedly

## Australian Injectable Drugs Handbook

https://aidh.hcn.com.au/

There is no data for Glycine with AIDH

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