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B12 SHOT METHYLCOBALAMIN 5ML VIAL 25MG/ML INJ SOLN
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# B12 SHOT METHYLCOBALAMIN 5ML VIAL 25MG/ML INJ SOLN ## Product Information **Drug:** Methylcobalamin (active form of Vitamin B12) **Concentration:** 25 mg/mL (25,000 mcg/mL) **Vial size:** 5 mL (total = 125 mg = 125,000 mcg) **Route:** IM or IV when given in B Complex Plus **Frequency:** Every 6 weeks DEPENDING ON BLOOD WORK UP ## Clinical Benefits - Energy production & metabolism: coenzyme for ATP synthesis - Nervous system health: supports myelin, neuropathy, cognition, memory - Mood support: cofactor in neurotransmitter pathways - Methylation & detoxification: works with folate in methyl cycle - Red blood cell formation: prevents megaloblastic anaemia ## Safety & Precautions - Very safe profile, water-soluble, excess excreted in urine - Rare: acneiform eruptions, mild diarrhoea, anxiety, or restlessness at very high doses - Pink-red urine common for 12–24 hours after infusion - Always dilute — avoid undiluted IV push due to vein irritation risk ## Australia Injectable Drugs Handbook https://aidh.hcn.com.au/browse/c/cyanocobalamin - No Incompatibilities ### STABILITY Store below 25 °C. Protect from light. Do not refrigerate or freeze.1. ### REFERENCES 1. Product information. Available from www.tga.gov.au. Accessed 24/08/2022. 2. Lexicomp pediatric and neonatal dosage handbook. 29th ed. Hudson, OH: UpToDate Inc; 2022-2023. 3. ASHP Injectable drug information 2021. Bethesda, MD: American Society of Health-System Pharmacists; 2021.
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