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# NEW NAD+ PROTOCOL

## Combined Protocol (IV + IM/SC)

A very popular clinical structure:

### Phase 1 – NAD+ Loading

- 250–500mg IV
- 1–2× weekly × 2–4 weeks
- **PLUS** 100–200mg SC on non-IV days (loading dose)

### Phase 2 – Stabilisation

- 500–750mg IV every 2–4 weeks
- **OR** 150–250mg IM weekly (stabilisation dose)

### Phase 3 – Maintenance

- Monthly IV or weekly IM

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## Contraindications & Precautions

❌ Pregnancy & breastfeeding

❌ Severe anxiety disorder (relative – may worsen during infusion)

❌ Uncontrolled hypertension

❌ Active infection

❌ Severe liver or renal dysfunction

❌ Acute migraines during infusion season

### Caution

- SSRIs, SNRIs, antipsychotics → monitor for overstimulation
- Beta-blockers → may mask physiological response
- Thyroid disorders → NAD+ may alter energy perception

## Side Effects

Usually rate-dependent:

- Nausea
- Chest tightness
- Head pressure
- Tingling
- GI discomfort
- Warmth/flushing
- Anxiety or "wired" sensation
- Fatigue post infusion (rare)

**Manage by slowing rate** — symptoms disappear in minutes - keep rate slow

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