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# ZINC

## Product Information

**Drug:** Zinc chloride

**Concentration:** 10.6 mg / 2 mL (≈ 5.3 mg/mL zinc chloride ≈ 5 mg/mL elemental zinc)

**Form:** Injection solution for IV use

**Supplied by:** Phebra (Australia)

## Clinical Uses

Zinc is an essential trace element for:

- Immune function (T-cell activity, wound healing, antioxidant support)
- Enzyme activity (DNA synthesis, growth, repair)
- Skin, hair, and nail health

In IV therapy, zinc is sometimes added to "wellness drips" as a trace mineral to support immunity and recovery.

## Dosage & Protocols (General Guidance)

### Therapeutic Use:

- **Adults:** 2.5–5 mg elemental zinc per day IV
- Higher doses (up to 12–15 mg/day) may be used in cases of deficiency, trauma, burns, or high losses (under medical supervision)

### IV Wellness Use:

- **Common dose:** 2.5–5 mg elemental zinc
- **Equivalent volume:**
- 0.5 mL = 2.5 mg
- 1 mL = 5 mg
- Typically added to: 250–500 mL carrier fluid (e.g., Normal Saline or Compound Sodium Lactate)
- **Wellness frequency** is weekly to fortnightly

## Australian Injectable Drug Handbook

https://aidh.hcn.com.au/browse/z/zinc_chloride

### STABILITY

Store below 25 °C.1

Incompatibilities - No information

### REFERENCES

1. Product information. Available from www.tga.gov.au. Accessed 11/05/2023.
2. Medical information. Confirmation of pH of several Phebra products [email]. Lane Cove West, NSW: Phebra Pty Ltd; 14/10/2022.
3. Lexicomp pediatric and neonatal dosage handbook. 29th ed. Hudson, OH: UpToDate Inc; 2022-2023.

## Common & Mild Adverse Reactions

These are usually infusion-rate related and transient:

- Metallic taste in mouth
- Nausea
- Mild abdominal discomfort
- Headache
- Flushing / warmth
- Lightheadedness

## Local Infusion Reactions

- Venous irritation
- Burning along vein
- Phlebitis
- Extravasation discomfort

➡ Zinc is moderately irritating to veins.

➡ Always dilute adequately and avoid rapid bolus.

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